Zhenhua Liu   Joint Center for Single Cell Biology, School of  Agriculture and Biology, Shanghai Jiao Tong University, 800 Dongchuan Rd., Shanghai 200240, China Email: zhenhua.liu@sjtu.edu.cn Lab website: https://zlab.sjtu.edu.cn/

 

 

Research Interest:

1, Evolution of plant metabolism--How plants have evolved astounding metabolic diversity?

2, Genomic structural basis underpinning metabolic diversification in plants.

3, Pathway elucidation and synthetic biology for plants with important medicinal uses.

4, Chemical ecology—decoding the chemical language of plants.

 

 

Selected Publications (# First author; # Corresponding author):

 

Xuan Zhou#, Zhenhua Liu*. Unlocking Plant Metabolic Diversity: A (pan)-Genomic View. Plant Communications, https://doi.org/10.1016/j.xplc.2022.100300. (2022).

 

Wenbing Su^#, Yi Jing^#, Shoukai Lin^#, Zhen Yue^#, Xianghui Yang^#, Jiabao Xu, Jincheng Wu, Zhike Zhang, Rui Xia, Jiaojiao Zhu, Ning An, Haixin Chen, Yanping Hong, Yuan Yuan, Ting Long, Ling Zhang, Yuanyuan Jiang, Zongli Liu, Hailan Zhang, Yongshun Gao, Yuexue Liu, Hailan Lin, Huicong Wang, Levi Yant, Shunquan Lin* and Zhenhua Liu*. Polyploidy underlies co-option and diversification of biosynthetic triterpene pathways in the apple tribe. PNAS. 118.20, e2101767118. (2021).

Shicheng Zou^#, Jincheng Wu^#, Muhammad Qasim Shahid, Yehua He, Shunquan Lin, Zhenhua Liu* & Xianghui Yang*. Identification of key taste components in loquat using widely targeted metabolomics. Food Chemistry, https://doi.org/10.1016/j.foodchem.2020.126822 (2020).

Zhenhua Liu^#, Jitender Cheema, Marielle Vigouroux, Lionel Hill, James Reed, Pirita Paajanen, Levi Yant and Anne Osbourn*. Formation and diversification of a paradigm biosynthetic gene cluster in plants. Nature Communications.11(1) 5354. doi:10.1038/s41467-020-19153-6. (2020).

Zhenhua Liu^#, Hernando G. Suarez Duran#, Yosapol Harnvanichvech, Michael J. Stephenson, M. Eric Schranz, David Nelson, Marnix H. Medema* and Anne Osbourn*. Drivers of metabolic diversification: How dynamic genomic neighborhoods generate new biosynthetic pathways in the Brassicaceae. New Phytologist, doi: 10.1111/nph.16338 (2019).

Zhenhua Liu^#, Raquel Tavarez, Evan S. Forsythe, Francois André, Raphaël Lugan, Gabriella Jonasson, Stéphanie Boutet Mercey, Takayuki Tohge, Mark Beilstein, Danièle Werck-Reichhart*, Hugues Renault. Evolutionary interplay between sister cytochrome P450 genes shapes plasticity in plant metabolism. Nature Communications. 7, 13026 doi: 10.1038/ncomms13026 (2016).

Zhenhua Liu^#, Benoît Boachon, Raphaël Lugan, Raquel Tavares, Mathieu Erhardt, Jérôme Mutterer, Valérie Demais, Stéphanie Pateyron, Véronique Brunaud, Toshiyuki Ohnishi, Ales Pencik, Patrick Achard, Fan Gong, Peter Hedden, Danièle Werck-Reichhart*, Hugues Renault. A conserved cytochrome P450 evolved in seed plants regulates flower maturation. Molecular Plant. 10.1016/j.molp.2015.09.002 (2015).

Zhenhua Liu^#, Wenjie Bao, Wanqi Liang, Jingyuan Yin, Dabing Zhang*. Identification of gamyb-4 and analysis of the regulatory role of GAMYB in rice anther development. Journal of Integrative Plant Biology. 52, 670-678. (2010).